arachidonic acid

[sakurakilla]

Nu lees ik heel veel over deze zuur... Zit in veel supplementen nu

wat doe het eingelijk

[Been]

Dit plukte ik via google

Syntrax heeft het geheim van de spieropbouwende werking van rood vlees ontdekt met Hyper H! Krachtsporters weten al tientallen jaren dat rood vlees spierkracht en spiermassa opbouwt. Hyper H is ontworpen om de verborgen kracht van rood vlees bloot te leggen. Naast Creatine bevat rood vlees nog een zeer krachtige stof; Arachidonic Zuur. Arachidonic Zuur zorgt ervoor dat je spieren meer eiwitten op gaan nemen. Met andere woorden, Arachidonic Zuur zorgt ervoor dat je spieren gaan groeien!

[sakurakilla]

die Hyper H van syntrax is een flop geworden van alles te laaag gedoseerd

maar ik heb dit gevonden heel interresant

Arachidonic acid is the principle building block for the synthesis of dienolic prostaglandins including PGE2 and PGF2. These prostaglandins are intimately involved with protein synthesis and muscle hypertrophy after exercise (2,3). Arachidonic acid is specifically correlated with amplified IGF-1 (Insulin-Like Growth Factor) signaling (4), enhanced satellite cell activation and proliferation (5), increased muscle cell regeneration and repair (6), enhanced androgen receptor synthesis (7), increased Nitric Oxide formation (8), and improved insulin sensitivity (9). Other benefits include possible long-term improvements in vascularity via stimulation of angiogenesis (blood vessel regeneration) in trained muscles (10), PPAR beta/delta agonist properties, which increase uncoupling proteins for a thermogenic effect (11), and inhibition of stearoyl-CoA desaturase-1 (12), which is strongly correlated with negative nutrient partitioning in humans; paving the way for AA to improve body composition (lean vs. fat mass). On top of all this, arachidonic acid inhibits resistin (13)

Who needs it?
Regular exercise can reduce arachidonic acid levels (16,17) and the production of anabolic prostaglandins (18), supporting the need for AA supplementation during intense weight training or athletic performance. Arachidonic acid is most commonly used by weight-training individuals, bodybuilders, and athletes in sports where enhanced anaerobic (short, rapid burst) performance is required. Reduced arachidonic acid levels are associated with "training stagnation", or a declining ability to stimulate muscle growth, strength gains, and delayed-onset muscle soreness (DOMS) following exercise.
How much should be taken? Are there any side effects?
The optimal dosage may vary with each individual and their particular goals. Use typically ranges from 75mg-250mg per day for long-term supplementation and anabolic support, to as much as 500mg-1000mg per day for a more rapid anabolic effect. During use some people notice increased muscle soreness, sore joints, headaches, or insomnia. Most users do not notice any significant side effects.
Is It Safe?
Yes, arachidonic is a natural and important essential fatty acid (EFA), and is safe for healthy people to take. The supplementation of doses as high as 1,500-1,700mg per day should not cause a change in HDL, LDL, or total cholesterol values, immune system functioning, or platelet aggregation values. (19,20,21) Furthermore, it is safe on all of the basic markers of health including lipids, blood pressure, blood cell counts, immune system mediators, and liver enzymes (22).
Who Shouldn't Take Arachidonic Acid?
Sedentary (inactive) individuals should not supplement with AA unless a dietary need has been identified, as deficiency in this group is not common. AA is an "as needed" pro-inflammatory by the body, so individuals with an injury may find that supplementation increases localized pain or soreness. AA supplementation is also not recommended during pregnancy, or by individuals with a history of diabetes, asthma, high blood pressure, high cholesterol, arthritis, heart disease, stroke, colitis, irritable bowel syndrome, cancer, prostate enlargement, or any inflammatory disease. As with most dietary supplements, you should seek a physician's approval before use if you are taking any medication(s), or suffer from any disease.
REFERENCES
U.S. Patent # 6,841,573. Use of arachidonic acid as a method of increasing skeletal muscle.
Trappe TA, Fluckery JD, White F, Lambert CP, Evans WJ. Skeletal muscle PGF (2) (alpha) and PGE (2) in response to eccentric resistance: influence of ibuprofen acetaminophen. J Clin Endocrinol Metab, 2001 Oct; 86 (10): 5067-70.
Soltov QA, Betters JL, Sellman JE, Lira VA, Long JH, Criswell DS. Ibuprofen inhibits skeletal muscle hypertrophy in rats. Med Sci Sports Exerc. 2006 May; 38 (5) : 840-6.
Phosphatidylinositol 3-kinase and p70 s6 kinase participate in the regulation of protein turnover in skeletal muscle by insulin and insulin-like growth factor I. Dardevet d, Sornet C, Vary T, Grizard J. Endocrinology. 1996 Oct;137(10):4087-94
Bondesen BA, Mills ST, Pavlath GK. The COX-2 pathway regulates growth of atrophied muscle via multiple mechanisms. Am J Physiol Cell Physiology 2006 Jun; 290(6): C1651-9. Epub 2006 Feb 8.
Bondesen BA, Mills ST, Kegley KM, Paylath GK. The COX-2 pathway is essential during early stages of skeletal muscle regeneration. Am J Phsyiol Cell Physiol. 2004 Aug; 287 (2): C475-83 Epub 2004 Apr 14.
Dietary effects of arachidonic-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression. Berger A, Mutch DM, Bruce German J, Roberts MA. Lipids Health Dis. 2002 Oct 21;1(1):2.
Specific effect of arachidonic acid on inducible nitric oxide synthase mRNA expression in human osteoblastic cells. Priante G, Musacchio E, Pagnin E, Calò LA, Baggio B. Clin Sci (Lond). 2005 Aug;109(2):177-82.
Borkman M, Storlien LH, Pan DA, Jenkins AB, Chrisholm DJ, Campbell LV. The relationship between insulin sensitivity and the fatty acid composition of skeletal muscle phospholipids. N Engl J Med. 1993 Jan 28;328(4):238-44
Tamura K, Sakuri T, Kogo H. Relationship between prostaglandin E2 and vascular endothelial growth factor (VEGF) in angiogenesis in human vascular endothelial cells. Vascul Pharmacol. 2006 Jun; 44 (6) : 411-6. Epub 2006 May 2.
Chevillotte E, Rieusset J, Roques M, Desage M, Vidal H. The regulation of uncoupling protein-2 gene expression by omega-6 polyunsaturated fatty acids in human skeletal muscle cells involves multiple pathways, including the nuclear receptor peroxisome proliferator-activated receptor beta. J Biol Chem. 2001 Apr 6;276(14):10853-60. Epub 2001 Jan 12.
Mutch DM, Grigorov M, Berger A, Fay LB, Roberts MA, Watkins SM, Willaimson G, German JB. An integrative metabolism approach identifies stearoyl-CoA desaturase as a target for an arachidonate-enriched diet. FASEB J. 2005 Apr;19(6):599-601. Epub 2005 Jan 24.
Haugen F, Zahid N, Dalen KT, Hollung K, Nebb HI, Drevon CA. Resistin expression in 3T3-L1 adipocytes is reduced by arachidonic acid. J Lipid Res. 2005 Jan; 46 (1): 143-53. Epub 2004 Oct 16.
Roberts, M, C Kerksick, L Taylor, M Iosia, B Campbell, C Wilborn, T Harvey, R Wilson, M. Greenwood, D Willoughby and R Kreider. Hormonal and intramuscular adaptations over 50 days of concomitant arachidonic acid supplementation and resistance training. Exercise & Sport Nutrition Laboratory, Center for Exercise, Nutrition & Preventive Health Research, Baylor University, Waco, TX 76798-7313.
** Official X-Factor Trial Summaries ** - Bodybuilding.com Forums (also appears in Body of Science Vol 1, Issue #3. September 2005)
Andersson, A, Sjodin A, Olsson R, Vessby B. Effects of physical exercise on phospholipid fatty acid composition in skeletal muscle. Am J Physiol. 1998 Mar;274(3 Pt 1):E432-8.
Andersson, A., A. Sjodin, A. Hedman, R. Olsson, and B. Vessby. Fatty acid profile of skeletal muscle phospholipids in trained and untrained young men. Am J Physiol Endocrinol Metab. 279:E744-751, 2000.
Effects of exercise on parameters of blood coagulation, platelet function and the prostaglandin system. Sinzinger H, Virgolini I. Sports Med, 1988 Oct;6(4):238-45. Review.
Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Kyle D. The effect of dietary arachidonic acid on platelet fatty acid composition, and blood coagulation in humans. Lipids. 1997 Apr; 32(4): 421-5.
Kelley DS, Taylor PC. Nelson GJ, Schmidt PC, Makey BF, Kyle D. Effects of dietary arachidonic acid on human immune response. Lipids. 1997 Apr; 32(4): 449-56.
Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Phinney SD, Kyle D, Silbermann S, Schaefer FJ. The effect of dietary arachidonic acid on plasma lipoprotein distributions, apoproteins, blood lipid levels, and tissue fatty acid composition in humans. Lipids. 1997 Apr; 32940: 427-33.
Wilborn, C, M Roberts, C Kerksick, M Iosia, L Taylor, B Campbell, T Harvey, R Wilson, M. Greenwood, D Willoughby and R Kreider. Changes in whole blood and clinical safety markers over 50 days of concomitant arachidonic acid supplementation and resistance training. Exercise & Sport Nutrition Laboratory, Center for Exercise, Nutrition &

[GeneralIx]

Heb even die dubbele post van je verwijderd, maar verder een interessant stukje.

[sakurakilla]

ohh thanx wist niet dat dubbel was...

heb jij meer info erover kunnen vinden..want het schijnt dat als je deze zuur neemt dat je geen andere vetten mee mag combineren zoals visolie etc

[ijzer]

Dit ziet er reteinteressant uit! Zijn er al sups en gebruikerservaringen?

[sakurakilla]

Dit ziet er reteinteressant uit! Zijn er al sups en gebruikerservaringen?

wtf!! ging ff zoeken naar supps...blijkt dat ik dit al een keer gepost heb..waarbij niemand het interresant vondt

dit product bevat 250ml van dat zuur (is ook het eenige product die de hoogste dosering heeft)

Bodybuilding.com - Molecular Nutrition X-Factor - Arachidonic Acid! On sale now!
mijn traingspartner heeft het op de proef gezet tijdje terug en hij is bijna klaar met zijn 50 dagen cycle... hij heeft before and after pics

idd ik vind het wel interresant
mischien dat ik x-factor only ga 50 dagen en kijken of het zelfde effect bij mij heeft

[ijzer]

Nou ben ik natuurlijk erg benieuwd naar de progressie van je maat en de foto's!

[sakurakilla]

ik zie hem straks...dan vraag ik meteeeen foto's

[GeneralIx]

Die ander was alleen het fabrikantenverhaal, en dit is iets wetenschappelijker gefundeerd. Dat scheelt al een hoop. Verder ga ik het niet proberen als ik mijn visolie en olijfolie ervoor moet dumpen. Ga geen basis wegdoen voor een sup.

[ijzer]

Review: Molecular Nutrition's X-Factor: Is Arachidonic Acid A Potent Anabolic Compound?

lijkt niet erg veel te doen helaas.....

[sakurakilla]

netjes kevf...heel interresant
maar hij zegt beneden ook dit

So is X-Factor worth a try?
There's certainly a nice theory behind it, and there are success stories, although these are anecdotal. My "take" is that it could be useful for certain people, as outlined above. I also think it has a potential use (in lower amounts) as a general purpose supplement, for people who have limited intake of omega-6 fatty acids in their diets. Arachidonic acid is an important metabolite, after all, and should not be considered a "bad" fat, if it isn't consumed in excess by healthy people.

[sakurakilla]

zoals ik zei hier de fotos van hem
hij is nu op dag 57 (ik dacht korter)




hij gebruikte ook universal animal nitro, en universal animal mstack en alri wtf pump
en als whey gebruikte hij gwoon nectar

[sakurakilla]

en plasma jet vergetem te melden

[GeneralIx]

En hoe denk jij dan precies te kunnen meten welke kg spiermassa van welk supplement komt?