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Spermide en LIF, iemand ervaring hiermee ? ?
Spermidine:
Spermidine
Heads: The bad news is, this is made from living human sperm. The good news is, you can use your own. (Just kidding on both counts.)
Spermidine is actually a substance called apolyamine and is found in high concentrations in milk, soybeans, tea leaves, soy sauce and mushrooms. Through vast amounts of animal research, spermidine has been shown to increase the amount of nutrients your body is able to absorb from food. It also prevents muscle from breaking down, especially after a broken bone or other trauma. Theoretically, spermidine could decrease recovery time between workouts and prevent overtraining, allowing you to work out harder and more often
Tails: So far, studies on spermidine have been performed only on mice and chicks (the yellow furry kind). More human studies will be necessary before this substance becomes commercially available
LIF:
LIF
Heads: A substance that will probably never completely enter the mainstream but has received considerable attention nonetheless is leukemia inhibitory factor, or LIF.
In several animal experiments, LIF was shown to have a massive growth-enhancing effect on injured muscle tissue. In one Australian study, mice were given LIF after sustaining an injury to their quadriceps. After several days, the mice treated with LIF had muscle fibers that were up to 132 percent larger than those of the mice in the placebo group. Because LIF helps regenerate muscle tissue after an injury, it could have major ramifications on training. Potentially, LIF could speed up the repair process your muscles undergo after a workout. This means you could blast your legs or back or biceps more than once or twice a week without turning into a useless mass of Advil-popping inflamed tissue.
Tails: At this time, it's unclear whether LIF will be classified as a drug, thus making it difficult to acquire for most people. Regardless, the scientists in the supplement-company labs will undoubtedly try to get it out there.
Leukemia inhibitory factor (LIF) infusion stimulates skeletal muscle regeneration after injury: injured muscle expresses lif mRNA.
Barnard W, Bower J, Brown MA, Murphy M, Austin L.
Department of Biochemistry, Monash University, Clayton Victoria, Australia.
Leukemia inhibitory factor (LIF) is known to stimulate myoblast growth in culture via direct receptor mediated mechanisms, but it does not suppress myoblast fusion in vitro. We show here that LIF is also effective in vivo, using a muscle crush model. Administration of LIF to the site of the crush results in an increased rate of regeneration of the injured muscle. LIF stimulates an increase in the size of the muscle fibers rather than an increase in total number. Perfusion of 125I-labelled LIF (125I-LIF) at the site of the crush leads to uptake of the great majority of 125I-LIF into the muscle, which suggests that LIF is acting directly at the site of injury. Further, following crush injury LIF mRNA synthesis commences in the muscle. These data provide evidence that LIF is acting as a natural trauma factor in vivo and is actively involved in muscle regeneration.
Spermidine:
Spermidine
Heads: The bad news is, this is made from living human sperm. The good news is, you can use your own. (Just kidding on both counts.)
Spermidine is actually a substance called apolyamine and is found in high concentrations in milk, soybeans, tea leaves, soy sauce and mushrooms. Through vast amounts of animal research, spermidine has been shown to increase the amount of nutrients your body is able to absorb from food. It also prevents muscle from breaking down, especially after a broken bone or other trauma. Theoretically, spermidine could decrease recovery time between workouts and prevent overtraining, allowing you to work out harder and more often
Tails: So far, studies on spermidine have been performed only on mice and chicks (the yellow furry kind). More human studies will be necessary before this substance becomes commercially available
LIF:
LIF
Heads: A substance that will probably never completely enter the mainstream but has received considerable attention nonetheless is leukemia inhibitory factor, or LIF.
In several animal experiments, LIF was shown to have a massive growth-enhancing effect on injured muscle tissue. In one Australian study, mice were given LIF after sustaining an injury to their quadriceps. After several days, the mice treated with LIF had muscle fibers that were up to 132 percent larger than those of the mice in the placebo group. Because LIF helps regenerate muscle tissue after an injury, it could have major ramifications on training. Potentially, LIF could speed up the repair process your muscles undergo after a workout. This means you could blast your legs or back or biceps more than once or twice a week without turning into a useless mass of Advil-popping inflamed tissue.
Tails: At this time, it's unclear whether LIF will be classified as a drug, thus making it difficult to acquire for most people. Regardless, the scientists in the supplement-company labs will undoubtedly try to get it out there.
Leukemia inhibitory factor (LIF) infusion stimulates skeletal muscle regeneration after injury: injured muscle expresses lif mRNA.
Barnard W, Bower J, Brown MA, Murphy M, Austin L.
Department of Biochemistry, Monash University, Clayton Victoria, Australia.
Leukemia inhibitory factor (LIF) is known to stimulate myoblast growth in culture via direct receptor mediated mechanisms, but it does not suppress myoblast fusion in vitro. We show here that LIF is also effective in vivo, using a muscle crush model. Administration of LIF to the site of the crush results in an increased rate of regeneration of the injured muscle. LIF stimulates an increase in the size of the muscle fibers rather than an increase in total number. Perfusion of 125I-labelled LIF (125I-LIF) at the site of the crush leads to uptake of the great majority of 125I-LIF into the muscle, which suggests that LIF is acting directly at the site of injury. Further, following crush injury LIF mRNA synthesis commences in the muscle. These data provide evidence that LIF is acting as a natural trauma factor in vivo and is actively involved in muscle regeneration.
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