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I often scratch my head in bewilderment when I see saw palmetto used in muscle building products. Saw palmetto is a popular prostate health herbal supplement that works for its "anti-anabolic" activity.
In the prostate gland, testosterone is converted to dihydrotestosterone (DHT) to exert its primary anabolic and androgenic effects. One thing DHT does is stimulate prostate cells to grow. As a man ages, an imbalance can occur, that is, too much DHT, and the prostate becomes enlarged.
This usually starts to occur at age 50, and the condition that develops is called BPH (Benign Prostatic Hypertrophy, or Benign Prostatic Hyperplasia).
BPH primarily develops in the part of the prostate directly adjacent to the urethra, compared to carcinoma of the prostate, which develops in the peripheral parts of the prostate. This is why BPH is usually associated with urination problems, as the enlarged prostate tissues interfere with the flow of urine in the urethra.
Some of the bioactive substances in saw palmetto extracts inhibit the enzyme (5-alpha-reductase) that is responsible for the conversion of testosterone to DHT. This reduction in DHT in the prostate gland, reverses the overgrowth of prostate cells.
In experimental animals given saw palmetto it was observed by researchers that the size and weight of their genital organs were smaller when compared to animals that did not receive saw palmetto.
Some of these animal research studies indicated potential anti-fertility effects of saw palmetto. Saw palmetto taking animals also had a reduction of total body weight.
In humans, studies of young muscle building people taking saw palmetto supplements are rare, however, one well designed research study of resistance training young men determined no muscle or strength building effects from taking saw palmetto containing supplements, along with other supposedly anabolic supplements.
It is very important for young, developing males to consider avoiding the use of saw palmetto supplements, especially during puberty and early adulthood while their gonads are under peak development.
Finally, saw palmetto does not increase total testosterone in the body or free testosterone. The bioactive substances in saw palmetto may actually interfere with the function of testosterone by blocking the androgenic and anabolic receptor sites of cells that testosterone needs to bind with to turn on cellular protein synthesis.
Tests using tissue samples revealed that substances in saw palmetto actually reduced the tissue uptake of testosterone and dihydrotestosterone, which means saw palmetto bioactives blocked these anabolic hormones from entering cells, which is very anti-anabolic. So, while saw palmetto is very useful and effective for people who have BPH, it should be avoided when people who are training to be super-anabolic.
Bodybuilding.com - Avoiding The Anti-Anabolics For Maximum Muscle Growth!
In the prostate gland, testosterone is converted to dihydrotestosterone (DHT) to exert its primary anabolic and androgenic effects. One thing DHT does is stimulate prostate cells to grow. As a man ages, an imbalance can occur, that is, too much DHT, and the prostate becomes enlarged.
This usually starts to occur at age 50, and the condition that develops is called BPH (Benign Prostatic Hypertrophy, or Benign Prostatic Hyperplasia).
BPH primarily develops in the part of the prostate directly adjacent to the urethra, compared to carcinoma of the prostate, which develops in the peripheral parts of the prostate. This is why BPH is usually associated with urination problems, as the enlarged prostate tissues interfere with the flow of urine in the urethra.
Some of the bioactive substances in saw palmetto extracts inhibit the enzyme (5-alpha-reductase) that is responsible for the conversion of testosterone to DHT. This reduction in DHT in the prostate gland, reverses the overgrowth of prostate cells.
In experimental animals given saw palmetto it was observed by researchers that the size and weight of their genital organs were smaller when compared to animals that did not receive saw palmetto.
Some of these animal research studies indicated potential anti-fertility effects of saw palmetto. Saw palmetto taking animals also had a reduction of total body weight.
In humans, studies of young muscle building people taking saw palmetto supplements are rare, however, one well designed research study of resistance training young men determined no muscle or strength building effects from taking saw palmetto containing supplements, along with other supposedly anabolic supplements.
It is very important for young, developing males to consider avoiding the use of saw palmetto supplements, especially during puberty and early adulthood while their gonads are under peak development.
Finally, saw palmetto does not increase total testosterone in the body or free testosterone. The bioactive substances in saw palmetto may actually interfere with the function of testosterone by blocking the androgenic and anabolic receptor sites of cells that testosterone needs to bind with to turn on cellular protein synthesis.
Tests using tissue samples revealed that substances in saw palmetto actually reduced the tissue uptake of testosterone and dihydrotestosterone, which means saw palmetto bioactives blocked these anabolic hormones from entering cells, which is very anti-anabolic. So, while saw palmetto is very useful and effective for people who have BPH, it should be avoided when people who are training to be super-anabolic.
Bodybuilding.com - Avoiding The Anti-Anabolics For Maximum Muscle Growth!
,want als ik niet had gezegd dat het niet goed was ,had je het gewoon genomen omdat iedereen zei dat het wel kon!
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