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Kwam dit tegen, staat bij dat je het absoluut niet in de buurt van je darmen moet spuiten, buik -> darmen. Lees het ff:
Wat praktijk ervaring:
Pretty much felt like I had a bad case of the flu. It made me just want to sleep all day and I ran a high fever. Running to the bathroom five times a day really sucked. If I am going to use something for fat loss that makes me feel like shit I think dnp is a better choice.
On the positive side, it did give me some quality time alone in the bathroom , and the fat in my love handle is dead forever.
went 5x a day. Felt like Minced Dog Shit. I did get a good portion of my classwork done in the Roadhouse Outhouse. My injection sites throbed!! I mean hardcore, almost taking the Lord's name in vain throb. Ok maybe i did once or twice (fogive me God, lol). The worst was that feeling in my lungs. Overall, little fat loss, and I also got screwed up on my ab injection schedule, and now my lower left ab is slightly slimmer than my lower right ab. DNP was much better for fat loss, although it may not be painful, Im pretty sure you cant die from PGF2. Although sometimes i wish i would have. (Ga dus symetrisch te werk!!!!
Disclaimer: Discussion of pharmaceutical agents below is presented for information only. Nothing here is meant to take the place of advice from a licensed health care practitioner. Consult a physician before taking any medication.Many readers enjoyed my previous article about prostaglandins as muscle builders. This short introduction to prostaglandins produced critics, controversies and queries. Prostaglandins, especially PGF2 are no wonder drugs. They will not make you a Mr. Olympia in a matter of days. They do not represent a substitute for training. Neither are they free of side-effects. Some are benign while others are more worrying. Besides, PGF2 is tricky to manipulate. So by no means do I pretend to have uncovered the ultimate anabolics. There is one fact though that cannot be denied: prostaglandins are very potent anabolic substances. It is true that thousands of champions were able to build their muscle mass without it, but we are living in a society in which the extra edge is always needed to more quickly achieve or exceed your goals. This is why I am going to discuss the pros and cons as well as the how-to of prostaglandins.
Among the most potent growth factors produced locally in the muscles are the prostaglandins. These quasi-hormones use fats as their raw materials. Several classes of prostaglandins exist. We will mainly focus on the most
potent one, namely the prostaglandin F2 alpha or PGF2 for short. If you apply PGF2 to a muscle cell, you are going to trigger a very strong anabolic response. PGF2 has been used by veterinarians for years not only to get animals pregnant but also to make them grow. A few daredevils figured out that if it was making animals more muscular, it would make
bodybuilders bigger too. This was a big leap of faith as many drugs produce wonderful effects in animals only to fail miserably in bodybuilders. Clenbuterol is a good example of this: ultra potent in animals, deceptive in
humans. Amazingly enough, this time it worked wonders.
WARNING:
What I am going to reveal is true for men ONLY. Women will not get any "benefit" from what I will describe below. Further, no women should EVER touch this drug which will induce a very severe pain in their ovaries. As
men do not have ovaries, this is something that will not happen to them. Ill side effect most probably will occour in males as well.
PGF2 and anabolism.
Many studies have demonstrated an anabolic effect of PGF2 in skeletal muscles of both humans and animals. Paradoxically, PGF2 usage is still reserved to a bodybuilding elite and no one is willing to
divulge the precious secret edge. One of the most remarkable effects of PGF2 is that it mediates the
major part of the anabolic effects of insulin. By using PGF2, you can use far less insulin and get a
far stronger muscle building effect.
PGF2 and weak bodyparts.
The cardinal rule of PGF2 is to inject as far away as possible from the intestine. You see, PGF2 induces a very strong contraction of the intestine and the bladder (both smooth muscles). The major candidate as a site of injection was the front shoulders. But by repeating injections in
the shoulders, bodybuilders soon ended up with grossly overdeveloped front delts. They looked like walking monkeys. The rest of their body was growing too, but not as fast as the muscles closest to the sites of
injections. What this means is that if one wants to develop a weak muscle, just inject PGF2 locally and watch
the muscle grow. We are talking about a real muscle growth and not an artificial swelling like Synthol or Esiclene would induce. Calves are a muscle of choice. In fact, even if your calves failed to grow no matter how much ******* and training you administered, PGF2 will solve your problem.
After a single cycle of PGF2, unresponsive calves start to respond to both training and *******s
even if they never did before.
The localized growth induced by PGF2 may appear magical, but there is a simple explanation. The
life cycle of the injected PGF2 is terribly short (minutes). Most of it will be destroyed in your lungs.
If you hit your right calf for example, this muscle will be exposed to a maximal concentration of
PGF2. As the prostaglandin rapidly leaks out of the calf and passes into the blood, it will quickly
reach the lungs where most of it will be destroyed. What is left of the PGF2 will be dispatched
evenly though your whole body. It means that the other muscles will be exposed to far less of the
anabolic effects of PGF2. So unless you want to make a weak point grow, you should rotate the
sites of injections frequently which as we will see is not a problem.
PGF2 is not to be confused with steroids.
You've probably realized by now that PGF2 produces growth in a radically different way from
*******s -- although I do not exclude that part of the anabolic actions of androgens are mediated by a
local release of PGF2. The way PGF2 should be used is therefore radically different from that of
androgens. ******* use is comparitively comfortable. You inject or swallow them once in a while and wait
for the growth to occur. This is not the case with PGF2. Their main drawback is precisely their
difficulty of administration. *******s once injected survive several days in your body. PGF2 will last
only several minutes though their stimulatory actions on anabolism will be far longer lasting
(hours). It means that frequent injections are compulsory for significant effect. Ideally this would be five times per day,30 minutes after meals. You will also notice that once you have injected PGF2, the muscle which received it gets sore almost immediately. If the muscle was already sore from training, that painful sensation may
become very intense. You definitely do not want to repeat injections at the very same location,
hence the necessity for rotation. By the same token, you will notice that you cannot inject in a
muscle and then train this muscle. PGF2 is algesic (a pain mediator). Therefore, the timing of
injections is key. You should wait for at least 2 to 3 days after you have trained a muscle to inject
it. Then you will have to wait for 24 hours before training this muscle. If your muscle is already
sore, It is advised not to use it as a site of injection as long as it hurts if it is to be used at all.
You will also learn that it is more comfortable to hit the outer part of the muscle than the inner part.
For example, it is less painful to hit the outer head of the triceps than the inner head that touches
your lats. Some bodyparts such as the biceps, the back, etc. are especially sensitive to the pain
sensation PGF2 will induce.
What about fat: PGF2 vs DNP?
We are told that DNP is the strongest thermogenic (temperature elevating) drug available. I dispute
this statement. Inject PGF2, wait for ten minutes and you will sweat profusely. In fact, your body
temperature will rise so much that you may feel very cold while a witness will get scared as you
feel so hot. By elevating your body temperature, PGF2 will burn up your fat at an accelerated rate.
Furthermore, unlike muscle cells, fat cells do not like to be exposed to PGF2. As a result, they die.
Mark this well: unlike a classical diet which makes each fat cell shrink, PGF2 kills fat cells. With
PGF2, you can say goodbye to your excess adipose tissue.
What about stacking *******s with PGF2?
If PGF2 is so powerful, why not stack it along with *******s for maximal effect? It looks like a neat
idea until you try. PGF2 potentiates the effects of androgens on muscles most likely by increasing
androgen receptor level. *******s also increase the effects of PGF2 probably by increasing the
density of muscle PGF2 receptors. You will end up with a combination that is too powerful.
Within two or three days on PGF2, you will notice that your muscles get very tight. You cannot find
harder muscles than muscles from a PGF2 user. It looks and feels great until you try to train. Within
three to four reps even with an empty bar, your muscles will get so pumped that you will not be able
to move. In fact, your training poundage are likely to drop severely. I have witnessed someone going
from 3 reps at 500 pounds in the incline bench press, to failing at 6 reps at 130 after a week of
(serious) PGF2 administration plus *******s. Do not worry though, your muscles will grow and you
will be able to resume heavy training once PGF2 is stopped. This pumping effect is too exaggerated
if you take *******s along with PGF2. So it is best to use the prostaglandins to grow when you're off
the *******s.
Is PGF2 safe?
The answer is clearly no, but neither is the use of *******s, insulin, clenbuterol, etc. By the way,
PGF2 is absolutely invisible at any drug test. What kind of side effects to expect? The first ones -- if
we except the elevation of temperature -- are that it will empty your guts of whatever they contain.
So make sure you have unrestricted use of a bathroom. This is going to last around 20 minutes.
What you do not want is to inject PGF2 into a vein! Learn to do the aspiration test. PGF2 is to be
injected intramuscularly with an insulin needle if you are lean enough. This is going to hurt like ####
and for a very long time (up to an hour) if you inject into a vein. You also may feel as if you had
some kind of cold in your throat. It is due to the vasoconstricting effect PGF2 has in your lungs.
Vomiting is a reported side effect but I have never heard of it in men.
Dosages.
You should start with a pretty low dosage (a half milligram) and see what happens. From there,
build up VERY slowly. Then, the sky is the limit. You can inject what is normally needed for several
cows and survive but believe me, you do not want to go through this. Do not forget to keep the vials
refrigerated. If you are new to PGF2, for simplicity choose the natural form and not an analog. PGF2
analogs have several advantages over straight PGF2 in that they have a longer half life and less
side effects, but some of them have no anabolic properties while others are more potent than
straight PGF2. Do not take a chance on that.
To sum up, I would like to paraphrase what Dan Duchaine has said about ******* users...
PGF2 users: Healthy, who knows? Big and lean, yes!
Re: PGF2A + Esiclene + Winstrol
Prostaglandins
Among the most potent growth factors produced locally in the muscles are the prostaglandins. These quasi-hormones use fats as their raw materials. Several classes of prostaglandins exist. We will mainly focus on the most potent one, namely the prostaglandin F2 alpha or PGF2 for short. If you apply PGF2 to a muscle cell, you are going to trigger a very strong anabolic response. PGF2 has been used by veterinarians for years not only to get animals pregnant but also to make them grow. A few daredevils figured out that if it was making animals more muscular, it would make bodybuilders bigger too. This was a big leap of faith as many drugs produce wonderful effects in animals only to fail miserably in bodybuilders. Clenbuterol is a good example of this: ultra potent in animals, deceptive in humans. Amazingly enough, this time it worked wonders.
WARNING:
What I am going to reveal is true for men ONLY. Women will not get any benefit from what I will describe below. Further, no women should EVER touch this drug which will induce a very severe pain in their ovaries. As men do not have ovaries, this is something that will not happen to them.
PGF2 and anabolism.
Many studies have demonstrated an anabolic effect of PGF2 in skeletal muscles of both humans and animals. Paradoxically, PGF2 usage is still reserved to a bodybuilding elite and no one is willing to divulge the precious secret edge. One of the most remarkable effects of PGF2 is that it mediates the major part of the anabolic effects of insulin. By using PGF2, you can use far less insulin and get a far stronger muscle building effect.
PGF2 and weak bodyparts. The cardinal rule of PGF2 is to inject as far away as possible from the intestine. You see, PGF2 induces a very strong contraction of the intestine and the bladder (both smooth muscles). The major candidate as a site of injection was the front shoulders. But by repeating injections in the shoulders, bodybuilders soon ended up with grossly overdeveloped front delts. They looked like walking monkeys. The rest of their body was growing too, but not as fast as the muscles closest to the sites of injections. What this means is that if you want to develop a weak muscle, just inject PGF2 locally and watch the muscle grow. We are talking about a real muscle growth and not an artificial swelling like Synthol or Esiclene would induce. Calves are a muscle of choice. In fact, even if your calves failed to grow no matter how much steroid and training you administered, PGF2 will solve your problem. After a single cycle of PGF2, unresponsive calves start to respond to both training and steroids even if they never did before.The localized growth induced by PGF2 may appear magical, but there is a simple explanation. The life cycle of the injected PGF2 is terribly short (minutes). Most of it will be destroyed in your lungs. If you hit your right calf for example, this muscle will be exposed to a maximal concentration of PGF2. As the prostaglandin rapidly leaks out of the calf and passes into the blood, it will quickly reach the lungs where most of it will be destroyed. What is left of the PGF2 will be dispatched evenly though your whole body. It means that the other muscles will be exposed to far less of the anabolic effects of PGF2. So unless you want to make a weak point grow, you should rotate the sites of injections frequently which as we will see is not a problem.
PGF2 is not to be confused with steroids. You've probably realized by now that PGF2 produces growth in a radically different way from steroids -- although I do not exclude that part of the anabolic actions of androgens are mediated by a local release of PGF2. The way PGF2 should be used is therefore radically different from that of androgens. Steroid use is rather comfortable. You inject or swallow them once in a while and wait for the growth to occur. This is not the case with PGF2. Their main drawback is precisely their difficulty of administration. Steroids once injected survive several days in your body. PGF2 will last only several minutes though their stimulatory actions on anabolism will be far longer lasting (hours). It means that frequent injections are compulsory. Ideally this would be five times per day, 30 minutes after meals.
You will also notice that once you have injected PGF2, the muscle which received it gets sore almost immediately. If the muscle was already sore from training, that painful sensation may become very intense. You definitely do not want to repeat injections at the very same location, hence the necessity for rotation. By the same token, you will notice that you cannot inject in a muscle and then train this muscle. PGF2 is algesic (a pain mediator). Therefore, the timing of injections is key. You should wait for at least 2 to 3 days after you have trained a muscle to inject it. Then you will have to wait for 24 hours before training this muscle. If your muscle is already sore, I advise against using it as a site of injection as long as it hurts. You will also learn that it is more comfortable to hit the outer part of the muscle than the inner part. For example, it is less painful to hit the outer head of the triceps than the inner head that touches your lats. Some bodyparts such as the biceps, the back, etc. are especially sensitive to the pain sensation PGF2 will induce.
Is PGF2 safe?
The answer is clearly no, but neither is the use of steroids, insulin, clenbuterol, etc. By the way, PGF2 is absolutely invisible at any drug test. What kind of side effects to expect? The first ones -- if we except the elevation of temperature -- are that it will empty your guts of whatever they contain. So make sure you have unrestricted use of a bathroom. This is going to last around 20 minutes. What you do not want is to inject PGF2 into a vein! Learn to do the aspiration test. PGF2 is to be injected intramuscularly with an insulin needle if you are lean enough. This is going to hurt like #### and for a very long time (up to an hour) if you inject into a vein. You also may feel as if you had some kind of cold in your throat. It is due to the vasoconstricting effect PGF2 has in your lungs. Vomiting is a reported side effect but I have never heard of it in men.
Dosages.
The lowest possible "effective" dose should be used You should start with a low dosage no higher than (a half milligram) and see what happens. From there, build up VERY slowly. Then, the sky is the limit. You can inject what is normally needed for several cows and survive but believe me, you do not want to go through this and it is potentially deadly. Do not forget to keep the vials refrigerated. If you are new to PGF2, for simplicity choose the natural form and not an analog. PGF2 analogs have several advantages over straight PGF2 in that they have a longer half life and less side effects, but some of them have no anabolic properties while others are more potent than straight PGF2. Do not take a chance on that.
Disclaimer: Discussion of pharmaceutical agents below is presented for information only. Nothing here is meant to take the place of advice from a licensed health care practitioner. Consult a physician before taking any medication.
Many readers enjoyed my previous article about prostaglandins as muscle builders. This short introduction to prostaglandins produced critics, controversies and queries. Prostaglandins, especially PGF2 are no wonder drugs. They will not make you a Mr. Olympia in a matter of days. They do not represent a substitute for training. Neither are they free of side-effects. Some are benign while others are more worrying. Besides, PGF2 is tricky to manipulate. So by no means do I pretend to have uncovered the ultimate anabolics. There is one fact though that cannot be denied: prostaglandins are very potent anabolic substances. It is true that thousands of champions were able to build their muscle mass without it, but we are living in a society in which the extra edge is always needed to more quickly achieve or exceed your goals. This is why I am going to discuss the pros and cons as well as the how-to of prostaglandins.
Prostaglandins: a very important modulator of growth
Each of our muscle cells produces prostaglandins naturally and continuously. Each of our muscle cells contains prostaglandin receptors. A muscle failing to manufacture enough prostaglandins will rapidly waste away. Animal studies have shown that immunization against PGF2 impairs the muscle growth even though scientists were expecting it would boost anabolism. In humans, a reduction of muscle prostaglandin production is associated with wasting. The potent inhibitors of prostaglandin synthesis such as cortisol produce their wasting effects in great part by reducing the muscle production of prostaglandins, thus slowing protein synthesis rate.From a physiological point of view, prostaglandins are very important if not one of the ultimate growth mediators. All the problems arise from their mode of actions. The cells which need more prostaglandins manufacture them for their own consumption or for the nearby cells. Prostaglandins do not have to circulate like testosterone which is mostly an endocrine hormone. Once in the blood, prostaglandins are rapidly destroyed. Those major discrepancies mean that prostaglandins cannot be used in the same way as anabolic steroids.Once injected, steroids slowly pass into the blood. They will eventually find their ways to the muscles among other tissues. Steroid usage is therefore pretty simple: inject and wait. Because of both their very short life cycle and their very localized actions, prostaglandins are far harder to manipulate.
Fighting the side effects
PGF2 analogues
Just as testosterone has analogues such as nandrolone, so do prostaglandins. The analogues are an attempt to solve the problems caused by the original hormone or substance. Steroid molecules such as nandrolone or trenbolone were developed in the hope they would induce more favorable actions (anabolism) while producing less side effects (virilization) compared to testosterone. Researchers designed PGF2 analogues in order to address the three main problems inherent to PGF2. First: to increase its very short life cycle, second: to lessen the incidence of the numerous side effects associated with PGF2 usage, third: to ease prostaglandin usage by developing oral versions.
As with testosterone some analogues proved useless while others do have some interesting properties, at least in the test tube. I am not going to tell you which analogue is the best. The truth is that I don't know. I only have experience with the real thing. This may be disappointing but I am not going to lie just to look better.
Aspirin as an anti-prostaglandin
Aspirin or aspirin-like substances have the potential to reduce some of the side effects such as pain associated with PGF2 administration. However I tend to consider that the use of aspirin along with PGF2 weakens the overall anabolic effects without effectively fighting the side effects. This is true for the aspirin you can find in medication as well as the aspirin hidden in some ephedrine-caffeine stacks. I suggest that you avoid both of them. Several hypotheses could be advanced about the inhibiting effects of aspirin. Some research has shown that aspirin could block prostaglandin receptors. It may also impair the conversion of PGF2 to PGE2 which seems important for a maximal muscle building effect. I know that PGE2 is considered as a muscle enemy in the bodybuilding magazines, but the fact is that several studies have pointed out its usefulness in the bodybuilding process as a growth agent for the muscles. One last hypothesis is that PGF2 stimulates the subsequent natural release of muscle PGF2 or PGE2 which could further enhance the anabolic process. Aspirin would prevent this secondary anabolic secretion.
Preventing the local growth by rotating the sites of injections I consider the local growth induced by PGF2 as a side effect. As I said last month, it is due to a weakness of PGF2 (a very rapid degradation) rather than a magical effect. Unless you want to bring up a specific weak point, you should constantly rotate the sites of injections. One more restriction is that it is easy, for example, to inject PGF2 in some body part like the front shoulders but far harder in the inner side of the biceps. You should also make sure to avoid hitting too close to the intestine which exacerbates the gastro-intestinal discomfort caused by PGF2. Though close to the intestine, the front legs are a rather interesting and "easy" site of injections. You just may feel your quads "better" as you walk. I would suggest you mark all the possible injection sites you have in order to structure your injection pattern. If you have weak points, they should be hit more often than your strong bodyparts. No injecting your right calf will make your left calve grow to the same extent. Same thing with the gastronemius and the soleus. Hitting one will mostly make the injected muscle grow with a lesser stimulation for the nearby muscles. So for the calves only, we have at least 15 possible sites of injections. One on the upper, outer soleus, one for the lower, outer soleus and one for the lower inner part of the soleus. One or two for the front calves depending on your degree of development. For the gastronemius, you have both the upper and lower part of the outer side as well as the upper and lower parts of the inner/rear part. Of course, you can multiply that by two as you hopefully have 2 calves. I consider that you have the same number of sites on the upper legs. Avoid the abs, the lower back and maybe the forearms. Your triceps hold at least 6 sites and at least 4 for your biceps. Your shoulders have at least 12. If you are not too sensitive, you can manage 12 more on your chest. It is a total of at least 64 sites (excluding the back) to choose from every day.If you are not sure about the muscle locations, check with an anatomy chart to avoid hitting a tendon or a bone. Note carefully which side of the body you last hit so that you can shift from the right to the left and from the left to the right with each injection. If a friend of yours is willing to help you with the injections, it will increase the potential number of injection sites by adding your whole upper back and helping the right handed persons with their right side of their upper body (and the opposite for the left handed persons). You will always find a helping hand in the gym.The main problem with the rotation is to inject into muscles that you are not about to train or muscles that you trained recently. This is why training each bodypart seriously only once a week will ease our use of PGF2. Light pumping sessions should not interfere with the PGF2 rotation schedule as the mild pain should be bearable. In fact, during a light workout, having a soreness-like mild pain should help you feel the muscle contraction better and should enhance your focus on the trained muscles.As I said last month, you should wait for at least two to three days after training to inject PGF2 because of its pain promoting effect. This length of time depends upon the degree of trauma inflicted to the trained muscles. If your training was really traumatic (by including plenty of heavy negative reps), you may have to wait longer. But PGF2 users do not have to traumatize their muscles to get results. In fact, thanks to the muscle pump you will obtain with the light weights, you will not have to go too heavy. Your workouts are more likely to be non-traumatic, allowing you to inject after only two days after the workout.I also advised to stop injecting into a muscle 24 hours before retraining it. This means that you have a three day window of opportunity for a single muscle per week to soak it up with PGF2.
Here is a one week schedule example. It assumes that your upper body is lagging a bit compared to your legs and is therefore trained a bit more. The first muscle is the bodypart of the day and should be trained hard (but avoid overly traumatic techniques such as pure negative reps and super heavy weights). The second and sometimes third muscles are meant to be trained in a light high rep fashion for around 5 sets each. In the least column, the muscles receiving PGF2 are mentioned. You will note that even though there are days off training, it is best to administer PGF2 everyday. Again, this is due to the short life cycle of PGF2 which makes it necessary to repeat injections frequently.
Day Muscle of the day Pumping muscles of the day Muscles in which PGF2 can be administered for the day
Monday Back Chest Chest*, Arms
Tuesday Legs Shoulders Shoulders*, Arms
Wesnesday Chest Back Shoulders, Arms
Thursday Rest Rest Shoulders, Back.
Friday Arms Legs Back, legs*.
Saturday Shoulders Back, Chest Back*, legs, chest*
Sunday Rest Rest Legs, Chest
* Inject after training rather than before.
The dosage issue
Most readers are interested in an "ideal" dosage schedule. Unfortunately, such a miraculous schedule does not exist. Steroids have been used for decades, yet no one is able to come up with a one fits all, fail-safe schedule. Though some claim to know exactly how to use steroids and how to stack them, this is a lie. The same applies to PGF2. The ideal schedule does not exist. It is up to you to figure out which one suits you best. I can give you some guidelines but I am more able to tell you how not to use it than to prescribe its use. As mentioned last month, I suggest to start with half a milligram. At that dosage, not much should occur. Better to be safe than sorry. If everything goes well, go up to a milligram the next time. See what is happening. If you are fine, try 2 milligrams. I think you understand how to build up your dosage during the first days of your very first cycle. There is normally 25 mg of PGF2 per 5 milliliters. At 1 ml. (therefore 5 mg.), you should start to be able to tell the drug is working. I suggest not to go above 2 ml. per injection. If you are using 1 ml. five times a day, it means one vial a day (two if you use 2 ml.s). 5 ml. is the most I have ever heard with a single injection, but I consider it as a huge dosage. Maybe in 5 to 10 years, it will sound like a sissy dosage, but only time will help us determine an upper limit.
Lowering the required dosage One easy way to reduce the PGF2 dosage (and therefore the side effects) while optimizing the anabolic response is to administer PGF2 while insulin secretion is high. This means at meal time -- or more precisely after a meal. Insulin can trigger the muscle secretion of PGF2. This is probably how it produces anabolism. But insulin does not stop here: it increases the muscle sensitivity to the anabolic effects of PGF2. This is why you can reduce your PGF2 dosage if it is used at meal time or administered with insulin or an insulin booster. The dosages mentioned above already take into account the beneficial synergetic action of insulin on PGF2.
How often?
Due to its short life cycle, PGF2 has to be administered as often as possible for optimal effect. This makes it very uncomfortable to use but as I mentioned in the introduction, it is a potent yet not ideal drug to use. As most bodybuilders eat at least five times, it means that there are five opportunities per day for PGF2 administration. Of course this assumes that you have plenty of free time. Not everybody is a pro bodybuilder and you may not need (or want) to reach their degree of muscularity or to act like them. Administered only twice or three times a day along with your major meals, PGF2 will still perform its magic. I would not recommend less than twice a day. During week ends, you may have more time and so you may be able to increase the injection frequency. You can resume your twice a day schedule as you go back to work on Monday.
Just understand that the more often you inject PGF2, the longer time your muscles will be exposed to this anabolic substance. Let's assume the anabolic stimulation of a single PGF2 administration lasts for two hours. Of course, this figure depends upon the dosage: the higher the dose, the longer it lasts, as it will take more time for our body to degrade the prostaglandins. If you inject only twice a day, you will generate a total of four hours of intense anabolism per 24 hours. It means that 20 hours during the day are wasted. If you inject 5 times a day, you create 10 hours of intense anabolism per 24 hours.
Is this a strength or a weakness of PGF2 over steroids? You are exposed to steroids 24 hours per day (assuming you use injectables over orals). So, again steroids are more comfortable to use. But you may have noticed that the levels of most of our endogenous hormones fluctuate throughout the day. It prevents our muscles from downregulating their anabolic responses to the growth stimulating hormones. This is one of main the problem associated with the constant delivery of steroids. The time off PGF2 inherent in its short life cycle helps fight the tendency toward reduced anabolic response as time goes by. It is therefore a source of discomfort but also an advantage as far as results are concerned.
I am going to propose two schedules as examples. One will be for beginners who want to build up some lean muscles. The other is for more advanced bodybuilders who want to fill the gap between two steroid cycles.
The beginner schedule Inject PGF2 ex. (half a ml.) 30 minutes after the noon lunch. Inject the whole half a ml. at only one place. Your lunch should be high in proteins and carbs while low in fats. Make sure you have a serving of weight gainers at hand during the next two hours. This has two purposes. First, some people report a hypoglycemia-like feeling after PGF2. Of course this side effect should be countered. Eating a liquid meal generally makes them feel better. Second, whenever anabolism is elevated, so should be protein feeding frequency. Repeat a similar procedure after the evening meal. Change the side of injection. For the most daring, adding an insulin booster before the meals may be a good idea. ex. Glipizide (2.5 mg) but Glibenclamide (the insulin booster of reference) has been shown to lessen the incidence of side effects of PGF2 especially on the intestine. For Glibenclamide, start with the 1.25 mg pills and build up to the 2.5 mg. This makes it a smart stack to enhance anabolism while reducing side effects. Of course, you should be extra careful about the potential hypoglycemia so make sure you ingest some carbs every 30 minutes for the next two hours when it is time for the weight gainers. I suggest that you increase your creatine intake according to your PGF2 dosage as prostaglandins like most other anabolic substances accelerate the wasting of creatine. Go with at least 10 grams of creatine per day.
The advanced schedule
This is not a pro schedule. It should rather fit most of the readers' needs for muscles. As you taper off your steroid intake, slowly build up your PGF2 intake first in terms of dosage, then in terms of frequency. The animal studies suggest that PGF2 tends to depress testosterone secretion. But the PGF2 users usually get very "horny", which is a good sign, especially at the end of a steroid cycle. And do not discount the general hardening properties of PGF2 which amazingly is not restricted to skeletal muscles. Frequency of administration as well as dosage should be increased compared to beginners. You also have the choice between insulin injections and oral insulin boosters. Sticking with the oral booster may be wiser until you get more comfortable with the control of your glycemia. This is especially true as PGF2 will enhance the hypoglycemic effects of insulin. Wake up and have a liquid meal followed by a more solid meal within 30 minutes. Use that period for an insulin shot (start low with 5 UI and build up to no more than 15 UI per meal) or for oral Glipizide (2.5 to 5 mg). Prefer a long acting insulin to a short one. Wait for 15 minutes before your PGF2 (always start low and build up as you feel more comfortable). Repeat this procedure at lunch. Keep the liquid meal for after the lunch in case you feel hypoglycemia. Another reason to prefer Glipizide at that time is that you may get tired of the frequent injections. Repeat this procedure after training. You can use another PGF2 injection a bit before bedtime still with a meal but without the insulin or the booster. Some people who bad-mouth the prostaglandins argue that prostaglandins depress GH secretion. This is funny as the scientific literature points out the opposite. GH should be liberated overnight.
As you use more PGF2 than in the beginner cycle, go with at least 15 grams of creatine over 24 hours.
The science of cycling
The length of a PGF2 cycle is generally determined by default. The cycle usually lasts the whole time you want to be off steroids. It means it can go from between 24 hours to two months. Even though bodybuilders welcome a drug that allows them to grow while off steroids, most will get tired of using PGF2 after a while. They are usually happy to switch back to anabolics. A good rule of thumb is therefore to use PGF2 until you get tired of it. Again, there is no magic number here.
Yet many maintain a lighter intake of PGF2 centered around their weak bodypart. A lighter schedule includes one or two injections a day in a weak bodypart such as the calves to help bring them up but without having to go with all the trouble associated with normal PGF2 use.
To conclude, I again would like to quote Dan Duchaine about steroids in USH II:
"Rule #7: Most people who have taken massive amounts of steroids don't get sick, don't die, and don't go crazy.
Rule #8: ... Never assume that you are like 'most people' until you prove it."
This exact same rule apply to PGF2 users. Do not assume that PGF2 use is benign. PGF2 will affect every one of the cells composing your body. You are not immune from a rare, unexpected reaction. Please do not consider PGF2 usage lightly. We would not like to hear from you in the horror story section of a bodybuilding magazine.
Prostaglandins and their Discovery
Prostaglandins are part of a class of substances called eicosanoids. Eicosanoids are a group of substances derived from fatty acids and include prostaglandins, thromboxanes, and leukotrienes, all of which are formed from precursor fatty acids by the incorporation of oxygen atoms into the fatty acid chains. This reaction is called oxygenation and is carried out by cyclo-oxygenase enzymes. Prostaglandins and their metabolites have been found in virtually every tissue in the body.
The discovery of prostaglandins and determination of their structure began in 1930, when Raphael Kurzrok and Charles Lieb, both new York gynecologists, observed that human seminal fluid stimulates contraction of isolated uterine muscle. A few years later in Sweden, Ulf von Euler confirmed this report and noted that human seminal fluid also produces contraction in intestinal smooth muscle and lowers blood pressure when injected into the blood stream. It was Von Euler who came up with the name prostaglandin for this mysterious substance. The name prostaglandin seemed appropriate because he thought it originated in the prostate gland. Today, we know that prostaglandin production is not limited to the prostate, in fact, there is virtually no soft tissue in the body that doesn?t produce them. The name, however, has stuck with us through the years. If Von Euler had known his name for prostaglandins would still be with us into the next millennia, I?m sure he would have chosen to name them "Von Eulers" or "UVEs" instead of prostaglandins. By 1960, several specific prostaglandins had been isolated in pure crystalline form and their structures determined. Because our concern with prostaglandins involves primarily PGF2a, and perhaps PGE2, we will not go into detail about the myriad of other prostaglandins. Just know that prostaglandins are abbreviated "PG". The additional letter and numerical script indicate the type and series. The various types differ in the functional group present in the five-membered ring.
While scientists were studying the structure of these new compounds, other research was being done to determine their role in human physiology and their potential as drugs. Initially these compounds were extremely expensive to synthesize and/or isolate in sufficient quantities for research. In 1969, the price of prostaglandins dropped dramatically with the discovery that the gorgonian sea whip, or sea fan, is a rich source of prostaglandin-like materials. Now however, there is no need to rely on natural sources because chemists have developed highly effective laboratory methods for the synthesis of almost any prostaglandin or prostaglandin analog.
Thinking of using Lutalyse and/or PGF2A? I've been seeing this stuff pop up here and there and I'm not sure if people realize the potential hazards of this stuff?? Anyway.......if you have/are considering it......at least read this first:
Lutalyse:
Lutalyse is a veterinary drug that's coming into vogue with serious hardcore bodybuilders who'll stop at nothing to gain an "advantage" (even if it's not a real advantage). utalyse is made by Upjohn and is a prostaglandin (PGF2Aa).
PGF2a possibly mediates the endogenous insulin levels and is also a de facto thermogenic, as body temperature is increased after the administration of exogenous PGF2a. Unlike other fat burners, which only decrease the size of fat cells, PGF2a actually destroys them. Fat cells die when exposed to PGF2a.
Side effects associated with PGF2a use are an elevation in body temperature, vomiting, labored breathing and severe abdominal pain/cramping. As PGF2a vasoconstricts the blood vessels in the lungs, the user will feel a tightening in the chest. If you're an asthmatic, use of PGFa could very well put you into full respiratory arrest followed by death. Because PGF2a increases insulinogenic effects, hypoglycemia is a potential side effect.
PGF2a has a very short half-life in the body (only minutes) and most of it is metabolized in the lungs, thus making frequent injections necessary. PGF2a will almost always cause a very strong contraction of the intestine and bladder, emptying the stomach and intestines of all its contents. That's a nice way of saying you'll have explosive diarrhea.
Rumor has it that PGF2a will make training near impossible because of the pump that is created from this drug alone. One of the logistical drawbacks of PGF2a is the difficulty of administration. As it has such a short half-life, injections will be needed quite frequently. Lutalyse comes in a 5 ml (5 mg/ml) multi-dose vial. A single aspirin can render the effects of Lutalyse nonexistent, so most people who use this drug avoid aspirin and aspirin analogs.
Legit use of Lutalyse is by cattle farmers and ranchers. Farmers and ranchers will use this drug to induce abortions in barnyard animals. One-hundred percent of the idiots, uh, I mean, users, I spoke with told me that Lutalyse made them feel terrible. In short, this stuff could kill you, a lot faster that steroids ever could. I wouldn't suggest anyone try this stuff.
Is PGF2A for me?
Is PGF2A for everyone? Clearly not! Will it work? Yes! In this information, I will try to cover as much as possible about this drug. What I have put together here is based much upon personal experiences?. I feel no report can accurately prepare you for everything?. PGF2A is no exception!
PGF2A and Anabolism
Many studies have demonstrated an anabolic effect of PGF2A in skeletal muscles of both humans and animals. Paradoxically, PGF2A usage is still reserved to a bodybuilding elite and no one is willing to divulge the precious secret edge. One of the most remarkable effects of PGF2A is that it mediates the major part of the anabolic effects of insulin. By using PGF2A, you can use far less insulin and get a far stronger muscle building effect.
Is PGF2A safe?
The answer is clearly no, but neither is the use of steroids, insulin, clenbuterol, etc. By the way, PGF2A is invisible at any drug test. What kind of side effects to expect? The first ones -- if we except the elevation of temperature -- are that it will empty your guts of whatever they contain. So make sure you have unrestricted use of a bathroom. This is going to last around 20 minutes. What you do not want is to inject PGF2A into a vein! Learn to do the aspiration test. PGF2A is to be injected intramuscularly with an insulin needle if you are lean enough. This is going to hurt like #### and for a very long time (up to an hour) if you inject into a vein. You also may feel as if you had some kind of cold in your throat. It is due to the vasoconstriction effect PGF2A has in your lungs. Vomiting is a reported side effect but I have never heard of it in men.
PGF2A is not to be confused with steroids
You've probably realized by now that PGF2A produces growth in a radically different way from steroids -- although I do not exclude that part of the anabolic actions of androgens are mediated by a local release of PGF2A. The way PGF2A should be used is therefore radically different from that of androgens. Steroid use is rather comfortable. You inject or swallow them occasionally and wait for the growth to occur. This is not the case with PGF2A. Their main drawback is precisely their difficulty of administration. Steroids once injected survive several days in your body. PGF2A will last only several minutes though their stimulatory actions on anabolism will be far longer lasting (hours). It means that frequent injections are compulsory. Ideally, this would be five times per day, 30 minutes after meals.
You will also notice that once you have injected PGF2A, the muscle, which received it, gets sore almost immediately. If the muscle was already sore from training, that painful sensation may become very intense. You definitely do not want to repeat injections at the very same location, hence the necessity for rotation. Similarly, you will notice that you cannot inject in a muscle and then train this muscle. PGF2A is algesic (a pain mediator). Therefore, the timing of injections is key. You should wait for at least 2 to 3 days after you have trained a muscle to inject it. Then you will have to wait for 24 hours before training this muscle. If your muscle is already sore, I advise against using it as a site of injection as long as it hurts.
You will also learn that it is more comfortable to hit the outer part of the muscle than the inner part. For example, it is less painful to hit the outer head of the triceps than the inner head that touches your lats. Some bodyparts such as the biceps, the back, etc. are especially sensitive to the pain sensation PGF2A will induce.
PGF2A and Weak Bodyparts
The cardinal rule of PGF2A is to inject as far away as possible from the Intestine. You see, PGF2A induces a very strong contraction of the Intestine and the bladder (both smooth muscles). The major candidate as a site of injection was the front shoulder. But by repeating injections in the shoulders, bodybuilders soon ended up with grossly overdeveloped
Front delt's. They looked like walking monkeys. The rest of their body was growing too, but not as fast as the muscles closest to the sites of injections.
What this means is that if you want to develop a weak muscle, just inject PGF2A locally and watch! The muscle grows. We are talking about a real muscle growth and not an artificial swelling like Synthol or Esiclene would induce. Calves are a muscle of choice. In fact, even if your calves failed To grow no matter how much training you administered, PGF2A will
solve your problem. After a single cycle of PGF2A, unresponsive calves start to respond, even if they never did before!
The localized growth induced by PGF2A may appear magical, but there is a simple explanation. The life cycle of the injected PGF2A is terribly short (minutes). Most of it will .Be destroyed in your lungs. If you hit your right calf for example, this muscle will be exposed to a maximal concentration of PGF2A. As the prostaglandin rapidly leaks out of the calf and passes into the blood, it will quickly reach the lungs where most of it will be destroyed. What is left of the PGF2A will be dispatched evenly though you're whole body. It means that the other muscles will be exposed to far less of the anabolic effects of PGF2A. So unless you want to make a weak point grow, you should rotate the sites of injections frequently which is not a problem.
Grtz
Wat praktijk ervaring:
Pretty much felt like I had a bad case of the flu. It made me just want to sleep all day and I ran a high fever. Running to the bathroom five times a day really sucked. If I am going to use something for fat loss that makes me feel like shit I think dnp is a better choice.
On the positive side, it did give me some quality time alone in the bathroom , and the fat in my love handle is dead forever.
went 5x a day. Felt like Minced Dog Shit. I did get a good portion of my classwork done in the Roadhouse Outhouse. My injection sites throbed!! I mean hardcore, almost taking the Lord's name in vain throb. Ok maybe i did once or twice (fogive me God, lol). The worst was that feeling in my lungs. Overall, little fat loss, and I also got screwed up on my ab injection schedule, and now my lower left ab is slightly slimmer than my lower right ab. DNP was much better for fat loss, although it may not be painful, Im pretty sure you cant die from PGF2. Although sometimes i wish i would have. (Ga dus symetrisch te werk!!!!
Disclaimer: Discussion of pharmaceutical agents below is presented for information only. Nothing here is meant to take the place of advice from a licensed health care practitioner. Consult a physician before taking any medication.Many readers enjoyed my previous article about prostaglandins as muscle builders. This short introduction to prostaglandins produced critics, controversies and queries. Prostaglandins, especially PGF2 are no wonder drugs. They will not make you a Mr. Olympia in a matter of days. They do not represent a substitute for training. Neither are they free of side-effects. Some are benign while others are more worrying. Besides, PGF2 is tricky to manipulate. So by no means do I pretend to have uncovered the ultimate anabolics. There is one fact though that cannot be denied: prostaglandins are very potent anabolic substances. It is true that thousands of champions were able to build their muscle mass without it, but we are living in a society in which the extra edge is always needed to more quickly achieve or exceed your goals. This is why I am going to discuss the pros and cons as well as the how-to of prostaglandins.
Among the most potent growth factors produced locally in the muscles are the prostaglandins. These quasi-hormones use fats as their raw materials. Several classes of prostaglandins exist. We will mainly focus on the most
potent one, namely the prostaglandin F2 alpha or PGF2 for short. If you apply PGF2 to a muscle cell, you are going to trigger a very strong anabolic response. PGF2 has been used by veterinarians for years not only to get animals pregnant but also to make them grow. A few daredevils figured out that if it was making animals more muscular, it would make
bodybuilders bigger too. This was a big leap of faith as many drugs produce wonderful effects in animals only to fail miserably in bodybuilders. Clenbuterol is a good example of this: ultra potent in animals, deceptive in
humans. Amazingly enough, this time it worked wonders.
WARNING:
What I am going to reveal is true for men ONLY. Women will not get any "benefit" from what I will describe below. Further, no women should EVER touch this drug which will induce a very severe pain in their ovaries. As
men do not have ovaries, this is something that will not happen to them. Ill side effect most probably will occour in males as well.
PGF2 and anabolism.
Many studies have demonstrated an anabolic effect of PGF2 in skeletal muscles of both humans and animals. Paradoxically, PGF2 usage is still reserved to a bodybuilding elite and no one is willing to
divulge the precious secret edge. One of the most remarkable effects of PGF2 is that it mediates the
major part of the anabolic effects of insulin. By using PGF2, you can use far less insulin and get a
far stronger muscle building effect.
PGF2 and weak bodyparts.
The cardinal rule of PGF2 is to inject as far away as possible from the intestine. You see, PGF2 induces a very strong contraction of the intestine and the bladder (both smooth muscles). The major candidate as a site of injection was the front shoulders. But by repeating injections in
the shoulders, bodybuilders soon ended up with grossly overdeveloped front delts. They looked like walking monkeys. The rest of their body was growing too, but not as fast as the muscles closest to the sites of
injections. What this means is that if one wants to develop a weak muscle, just inject PGF2 locally and watch
the muscle grow. We are talking about a real muscle growth and not an artificial swelling like Synthol or Esiclene would induce. Calves are a muscle of choice. In fact, even if your calves failed to grow no matter how much ******* and training you administered, PGF2 will solve your problem.
After a single cycle of PGF2, unresponsive calves start to respond to both training and *******s
even if they never did before.
The localized growth induced by PGF2 may appear magical, but there is a simple explanation. The
life cycle of the injected PGF2 is terribly short (minutes). Most of it will be destroyed in your lungs.
If you hit your right calf for example, this muscle will be exposed to a maximal concentration of
PGF2. As the prostaglandin rapidly leaks out of the calf and passes into the blood, it will quickly
reach the lungs where most of it will be destroyed. What is left of the PGF2 will be dispatched
evenly though your whole body. It means that the other muscles will be exposed to far less of the
anabolic effects of PGF2. So unless you want to make a weak point grow, you should rotate the
sites of injections frequently which as we will see is not a problem.
PGF2 is not to be confused with steroids.
You've probably realized by now that PGF2 produces growth in a radically different way from
*******s -- although I do not exclude that part of the anabolic actions of androgens are mediated by a
local release of PGF2. The way PGF2 should be used is therefore radically different from that of
androgens. ******* use is comparitively comfortable. You inject or swallow them once in a while and wait
for the growth to occur. This is not the case with PGF2. Their main drawback is precisely their
difficulty of administration. *******s once injected survive several days in your body. PGF2 will last
only several minutes though their stimulatory actions on anabolism will be far longer lasting
(hours). It means that frequent injections are compulsory for significant effect. Ideally this would be five times per day,30 minutes after meals. You will also notice that once you have injected PGF2, the muscle which received it gets sore almost immediately. If the muscle was already sore from training, that painful sensation may
become very intense. You definitely do not want to repeat injections at the very same location,
hence the necessity for rotation. By the same token, you will notice that you cannot inject in a
muscle and then train this muscle. PGF2 is algesic (a pain mediator). Therefore, the timing of
injections is key. You should wait for at least 2 to 3 days after you have trained a muscle to inject
it. Then you will have to wait for 24 hours before training this muscle. If your muscle is already
sore, It is advised not to use it as a site of injection as long as it hurts if it is to be used at all.
You will also learn that it is more comfortable to hit the outer part of the muscle than the inner part.
For example, it is less painful to hit the outer head of the triceps than the inner head that touches
your lats. Some bodyparts such as the biceps, the back, etc. are especially sensitive to the pain
sensation PGF2 will induce.
What about fat: PGF2 vs DNP?
We are told that DNP is the strongest thermogenic (temperature elevating) drug available. I dispute
this statement. Inject PGF2, wait for ten minutes and you will sweat profusely. In fact, your body
temperature will rise so much that you may feel very cold while a witness will get scared as you
feel so hot. By elevating your body temperature, PGF2 will burn up your fat at an accelerated rate.
Furthermore, unlike muscle cells, fat cells do not like to be exposed to PGF2. As a result, they die.
Mark this well: unlike a classical diet which makes each fat cell shrink, PGF2 kills fat cells. With
PGF2, you can say goodbye to your excess adipose tissue.
What about stacking *******s with PGF2?
If PGF2 is so powerful, why not stack it along with *******s for maximal effect? It looks like a neat
idea until you try. PGF2 potentiates the effects of androgens on muscles most likely by increasing
androgen receptor level. *******s also increase the effects of PGF2 probably by increasing the
density of muscle PGF2 receptors. You will end up with a combination that is too powerful.
Within two or three days on PGF2, you will notice that your muscles get very tight. You cannot find
harder muscles than muscles from a PGF2 user. It looks and feels great until you try to train. Within
three to four reps even with an empty bar, your muscles will get so pumped that you will not be able
to move. In fact, your training poundage are likely to drop severely. I have witnessed someone going
from 3 reps at 500 pounds in the incline bench press, to failing at 6 reps at 130 after a week of
(serious) PGF2 administration plus *******s. Do not worry though, your muscles will grow and you
will be able to resume heavy training once PGF2 is stopped. This pumping effect is too exaggerated
if you take *******s along with PGF2. So it is best to use the prostaglandins to grow when you're off
the *******s.
Is PGF2 safe?
The answer is clearly no, but neither is the use of *******s, insulin, clenbuterol, etc. By the way,
PGF2 is absolutely invisible at any drug test. What kind of side effects to expect? The first ones -- if
we except the elevation of temperature -- are that it will empty your guts of whatever they contain.
So make sure you have unrestricted use of a bathroom. This is going to last around 20 minutes.
What you do not want is to inject PGF2 into a vein! Learn to do the aspiration test. PGF2 is to be
injected intramuscularly with an insulin needle if you are lean enough. This is going to hurt like ####
and for a very long time (up to an hour) if you inject into a vein. You also may feel as if you had
some kind of cold in your throat. It is due to the vasoconstricting effect PGF2 has in your lungs.
Vomiting is a reported side effect but I have never heard of it in men.
Dosages.
You should start with a pretty low dosage (a half milligram) and see what happens. From there,
build up VERY slowly. Then, the sky is the limit. You can inject what is normally needed for several
cows and survive but believe me, you do not want to go through this. Do not forget to keep the vials
refrigerated. If you are new to PGF2, for simplicity choose the natural form and not an analog. PGF2
analogs have several advantages over straight PGF2 in that they have a longer half life and less
side effects, but some of them have no anabolic properties while others are more potent than
straight PGF2. Do not take a chance on that.
To sum up, I would like to paraphrase what Dan Duchaine has said about ******* users...
PGF2 users: Healthy, who knows? Big and lean, yes!
Re: PGF2A + Esiclene + Winstrol
Prostaglandins
Among the most potent growth factors produced locally in the muscles are the prostaglandins. These quasi-hormones use fats as their raw materials. Several classes of prostaglandins exist. We will mainly focus on the most potent one, namely the prostaglandin F2 alpha or PGF2 for short. If you apply PGF2 to a muscle cell, you are going to trigger a very strong anabolic response. PGF2 has been used by veterinarians for years not only to get animals pregnant but also to make them grow. A few daredevils figured out that if it was making animals more muscular, it would make bodybuilders bigger too. This was a big leap of faith as many drugs produce wonderful effects in animals only to fail miserably in bodybuilders. Clenbuterol is a good example of this: ultra potent in animals, deceptive in humans. Amazingly enough, this time it worked wonders.
WARNING:
What I am going to reveal is true for men ONLY. Women will not get any benefit from what I will describe below. Further, no women should EVER touch this drug which will induce a very severe pain in their ovaries. As men do not have ovaries, this is something that will not happen to them.
PGF2 and anabolism.
Many studies have demonstrated an anabolic effect of PGF2 in skeletal muscles of both humans and animals. Paradoxically, PGF2 usage is still reserved to a bodybuilding elite and no one is willing to divulge the precious secret edge. One of the most remarkable effects of PGF2 is that it mediates the major part of the anabolic effects of insulin. By using PGF2, you can use far less insulin and get a far stronger muscle building effect.
PGF2 and weak bodyparts. The cardinal rule of PGF2 is to inject as far away as possible from the intestine. You see, PGF2 induces a very strong contraction of the intestine and the bladder (both smooth muscles). The major candidate as a site of injection was the front shoulders. But by repeating injections in the shoulders, bodybuilders soon ended up with grossly overdeveloped front delts. They looked like walking monkeys. The rest of their body was growing too, but not as fast as the muscles closest to the sites of injections. What this means is that if you want to develop a weak muscle, just inject PGF2 locally and watch the muscle grow. We are talking about a real muscle growth and not an artificial swelling like Synthol or Esiclene would induce. Calves are a muscle of choice. In fact, even if your calves failed to grow no matter how much steroid and training you administered, PGF2 will solve your problem. After a single cycle of PGF2, unresponsive calves start to respond to both training and steroids even if they never did before.The localized growth induced by PGF2 may appear magical, but there is a simple explanation. The life cycle of the injected PGF2 is terribly short (minutes). Most of it will be destroyed in your lungs. If you hit your right calf for example, this muscle will be exposed to a maximal concentration of PGF2. As the prostaglandin rapidly leaks out of the calf and passes into the blood, it will quickly reach the lungs where most of it will be destroyed. What is left of the PGF2 will be dispatched evenly though your whole body. It means that the other muscles will be exposed to far less of the anabolic effects of PGF2. So unless you want to make a weak point grow, you should rotate the sites of injections frequently which as we will see is not a problem.
PGF2 is not to be confused with steroids. You've probably realized by now that PGF2 produces growth in a radically different way from steroids -- although I do not exclude that part of the anabolic actions of androgens are mediated by a local release of PGF2. The way PGF2 should be used is therefore radically different from that of androgens. Steroid use is rather comfortable. You inject or swallow them once in a while and wait for the growth to occur. This is not the case with PGF2. Their main drawback is precisely their difficulty of administration. Steroids once injected survive several days in your body. PGF2 will last only several minutes though their stimulatory actions on anabolism will be far longer lasting (hours). It means that frequent injections are compulsory. Ideally this would be five times per day, 30 minutes after meals.
You will also notice that once you have injected PGF2, the muscle which received it gets sore almost immediately. If the muscle was already sore from training, that painful sensation may become very intense. You definitely do not want to repeat injections at the very same location, hence the necessity for rotation. By the same token, you will notice that you cannot inject in a muscle and then train this muscle. PGF2 is algesic (a pain mediator). Therefore, the timing of injections is key. You should wait for at least 2 to 3 days after you have trained a muscle to inject it. Then you will have to wait for 24 hours before training this muscle. If your muscle is already sore, I advise against using it as a site of injection as long as it hurts. You will also learn that it is more comfortable to hit the outer part of the muscle than the inner part. For example, it is less painful to hit the outer head of the triceps than the inner head that touches your lats. Some bodyparts such as the biceps, the back, etc. are especially sensitive to the pain sensation PGF2 will induce.
Is PGF2 safe?
The answer is clearly no, but neither is the use of steroids, insulin, clenbuterol, etc. By the way, PGF2 is absolutely invisible at any drug test. What kind of side effects to expect? The first ones -- if we except the elevation of temperature -- are that it will empty your guts of whatever they contain. So make sure you have unrestricted use of a bathroom. This is going to last around 20 minutes. What you do not want is to inject PGF2 into a vein! Learn to do the aspiration test. PGF2 is to be injected intramuscularly with an insulin needle if you are lean enough. This is going to hurt like #### and for a very long time (up to an hour) if you inject into a vein. You also may feel as if you had some kind of cold in your throat. It is due to the vasoconstricting effect PGF2 has in your lungs. Vomiting is a reported side effect but I have never heard of it in men.
Dosages.
The lowest possible "effective" dose should be used You should start with a low dosage no higher than (a half milligram) and see what happens. From there, build up VERY slowly. Then, the sky is the limit. You can inject what is normally needed for several cows and survive but believe me, you do not want to go through this and it is potentially deadly. Do not forget to keep the vials refrigerated. If you are new to PGF2, for simplicity choose the natural form and not an analog. PGF2 analogs have several advantages over straight PGF2 in that they have a longer half life and less side effects, but some of them have no anabolic properties while others are more potent than straight PGF2. Do not take a chance on that.
Disclaimer: Discussion of pharmaceutical agents below is presented for information only. Nothing here is meant to take the place of advice from a licensed health care practitioner. Consult a physician before taking any medication.
Many readers enjoyed my previous article about prostaglandins as muscle builders. This short introduction to prostaglandins produced critics, controversies and queries. Prostaglandins, especially PGF2 are no wonder drugs. They will not make you a Mr. Olympia in a matter of days. They do not represent a substitute for training. Neither are they free of side-effects. Some are benign while others are more worrying. Besides, PGF2 is tricky to manipulate. So by no means do I pretend to have uncovered the ultimate anabolics. There is one fact though that cannot be denied: prostaglandins are very potent anabolic substances. It is true that thousands of champions were able to build their muscle mass without it, but we are living in a society in which the extra edge is always needed to more quickly achieve or exceed your goals. This is why I am going to discuss the pros and cons as well as the how-to of prostaglandins.
Prostaglandins: a very important modulator of growth
Each of our muscle cells produces prostaglandins naturally and continuously. Each of our muscle cells contains prostaglandin receptors. A muscle failing to manufacture enough prostaglandins will rapidly waste away. Animal studies have shown that immunization against PGF2 impairs the muscle growth even though scientists were expecting it would boost anabolism. In humans, a reduction of muscle prostaglandin production is associated with wasting. The potent inhibitors of prostaglandin synthesis such as cortisol produce their wasting effects in great part by reducing the muscle production of prostaglandins, thus slowing protein synthesis rate.From a physiological point of view, prostaglandins are very important if not one of the ultimate growth mediators. All the problems arise from their mode of actions. The cells which need more prostaglandins manufacture them for their own consumption or for the nearby cells. Prostaglandins do not have to circulate like testosterone which is mostly an endocrine hormone. Once in the blood, prostaglandins are rapidly destroyed. Those major discrepancies mean that prostaglandins cannot be used in the same way as anabolic steroids.Once injected, steroids slowly pass into the blood. They will eventually find their ways to the muscles among other tissues. Steroid usage is therefore pretty simple: inject and wait. Because of both their very short life cycle and their very localized actions, prostaglandins are far harder to manipulate.
Fighting the side effects
PGF2 analogues
Just as testosterone has analogues such as nandrolone, so do prostaglandins. The analogues are an attempt to solve the problems caused by the original hormone or substance. Steroid molecules such as nandrolone or trenbolone were developed in the hope they would induce more favorable actions (anabolism) while producing less side effects (virilization) compared to testosterone. Researchers designed PGF2 analogues in order to address the three main problems inherent to PGF2. First: to increase its very short life cycle, second: to lessen the incidence of the numerous side effects associated with PGF2 usage, third: to ease prostaglandin usage by developing oral versions.
As with testosterone some analogues proved useless while others do have some interesting properties, at least in the test tube. I am not going to tell you which analogue is the best. The truth is that I don't know. I only have experience with the real thing. This may be disappointing but I am not going to lie just to look better.
Aspirin as an anti-prostaglandin
Aspirin or aspirin-like substances have the potential to reduce some of the side effects such as pain associated with PGF2 administration. However I tend to consider that the use of aspirin along with PGF2 weakens the overall anabolic effects without effectively fighting the side effects. This is true for the aspirin you can find in medication as well as the aspirin hidden in some ephedrine-caffeine stacks. I suggest that you avoid both of them. Several hypotheses could be advanced about the inhibiting effects of aspirin. Some research has shown that aspirin could block prostaglandin receptors. It may also impair the conversion of PGF2 to PGE2 which seems important for a maximal muscle building effect. I know that PGE2 is considered as a muscle enemy in the bodybuilding magazines, but the fact is that several studies have pointed out its usefulness in the bodybuilding process as a growth agent for the muscles. One last hypothesis is that PGF2 stimulates the subsequent natural release of muscle PGF2 or PGE2 which could further enhance the anabolic process. Aspirin would prevent this secondary anabolic secretion.
Preventing the local growth by rotating the sites of injections I consider the local growth induced by PGF2 as a side effect. As I said last month, it is due to a weakness of PGF2 (a very rapid degradation) rather than a magical effect. Unless you want to bring up a specific weak point, you should constantly rotate the sites of injections. One more restriction is that it is easy, for example, to inject PGF2 in some body part like the front shoulders but far harder in the inner side of the biceps. You should also make sure to avoid hitting too close to the intestine which exacerbates the gastro-intestinal discomfort caused by PGF2. Though close to the intestine, the front legs are a rather interesting and "easy" site of injections. You just may feel your quads "better" as you walk. I would suggest you mark all the possible injection sites you have in order to structure your injection pattern. If you have weak points, they should be hit more often than your strong bodyparts. No injecting your right calf will make your left calve grow to the same extent. Same thing with the gastronemius and the soleus. Hitting one will mostly make the injected muscle grow with a lesser stimulation for the nearby muscles. So for the calves only, we have at least 15 possible sites of injections. One on the upper, outer soleus, one for the lower, outer soleus and one for the lower inner part of the soleus. One or two for the front calves depending on your degree of development. For the gastronemius, you have both the upper and lower part of the outer side as well as the upper and lower parts of the inner/rear part. Of course, you can multiply that by two as you hopefully have 2 calves. I consider that you have the same number of sites on the upper legs. Avoid the abs, the lower back and maybe the forearms. Your triceps hold at least 6 sites and at least 4 for your biceps. Your shoulders have at least 12. If you are not too sensitive, you can manage 12 more on your chest. It is a total of at least 64 sites (excluding the back) to choose from every day.If you are not sure about the muscle locations, check with an anatomy chart to avoid hitting a tendon or a bone. Note carefully which side of the body you last hit so that you can shift from the right to the left and from the left to the right with each injection. If a friend of yours is willing to help you with the injections, it will increase the potential number of injection sites by adding your whole upper back and helping the right handed persons with their right side of their upper body (and the opposite for the left handed persons). You will always find a helping hand in the gym.The main problem with the rotation is to inject into muscles that you are not about to train or muscles that you trained recently. This is why training each bodypart seriously only once a week will ease our use of PGF2. Light pumping sessions should not interfere with the PGF2 rotation schedule as the mild pain should be bearable. In fact, during a light workout, having a soreness-like mild pain should help you feel the muscle contraction better and should enhance your focus on the trained muscles.As I said last month, you should wait for at least two to three days after training to inject PGF2 because of its pain promoting effect. This length of time depends upon the degree of trauma inflicted to the trained muscles. If your training was really traumatic (by including plenty of heavy negative reps), you may have to wait longer. But PGF2 users do not have to traumatize their muscles to get results. In fact, thanks to the muscle pump you will obtain with the light weights, you will not have to go too heavy. Your workouts are more likely to be non-traumatic, allowing you to inject after only two days after the workout.I also advised to stop injecting into a muscle 24 hours before retraining it. This means that you have a three day window of opportunity for a single muscle per week to soak it up with PGF2.
Here is a one week schedule example. It assumes that your upper body is lagging a bit compared to your legs and is therefore trained a bit more. The first muscle is the bodypart of the day and should be trained hard (but avoid overly traumatic techniques such as pure negative reps and super heavy weights). The second and sometimes third muscles are meant to be trained in a light high rep fashion for around 5 sets each. In the least column, the muscles receiving PGF2 are mentioned. You will note that even though there are days off training, it is best to administer PGF2 everyday. Again, this is due to the short life cycle of PGF2 which makes it necessary to repeat injections frequently.
Day Muscle of the day Pumping muscles of the day Muscles in which PGF2 can be administered for the day
Monday Back Chest Chest*, Arms
Tuesday Legs Shoulders Shoulders*, Arms
Wesnesday Chest Back Shoulders, Arms
Thursday Rest Rest Shoulders, Back.
Friday Arms Legs Back, legs*.
Saturday Shoulders Back, Chest Back*, legs, chest*
Sunday Rest Rest Legs, Chest
* Inject after training rather than before.
The dosage issue
Most readers are interested in an "ideal" dosage schedule. Unfortunately, such a miraculous schedule does not exist. Steroids have been used for decades, yet no one is able to come up with a one fits all, fail-safe schedule. Though some claim to know exactly how to use steroids and how to stack them, this is a lie. The same applies to PGF2. The ideal schedule does not exist. It is up to you to figure out which one suits you best. I can give you some guidelines but I am more able to tell you how not to use it than to prescribe its use. As mentioned last month, I suggest to start with half a milligram. At that dosage, not much should occur. Better to be safe than sorry. If everything goes well, go up to a milligram the next time. See what is happening. If you are fine, try 2 milligrams. I think you understand how to build up your dosage during the first days of your very first cycle. There is normally 25 mg of PGF2 per 5 milliliters. At 1 ml. (therefore 5 mg.), you should start to be able to tell the drug is working. I suggest not to go above 2 ml. per injection. If you are using 1 ml. five times a day, it means one vial a day (two if you use 2 ml.s). 5 ml. is the most I have ever heard with a single injection, but I consider it as a huge dosage. Maybe in 5 to 10 years, it will sound like a sissy dosage, but only time will help us determine an upper limit.
Lowering the required dosage One easy way to reduce the PGF2 dosage (and therefore the side effects) while optimizing the anabolic response is to administer PGF2 while insulin secretion is high. This means at meal time -- or more precisely after a meal. Insulin can trigger the muscle secretion of PGF2. This is probably how it produces anabolism. But insulin does not stop here: it increases the muscle sensitivity to the anabolic effects of PGF2. This is why you can reduce your PGF2 dosage if it is used at meal time or administered with insulin or an insulin booster. The dosages mentioned above already take into account the beneficial synergetic action of insulin on PGF2.
How often?
Due to its short life cycle, PGF2 has to be administered as often as possible for optimal effect. This makes it very uncomfortable to use but as I mentioned in the introduction, it is a potent yet not ideal drug to use. As most bodybuilders eat at least five times, it means that there are five opportunities per day for PGF2 administration. Of course this assumes that you have plenty of free time. Not everybody is a pro bodybuilder and you may not need (or want) to reach their degree of muscularity or to act like them. Administered only twice or three times a day along with your major meals, PGF2 will still perform its magic. I would not recommend less than twice a day. During week ends, you may have more time and so you may be able to increase the injection frequency. You can resume your twice a day schedule as you go back to work on Monday.
Just understand that the more often you inject PGF2, the longer time your muscles will be exposed to this anabolic substance. Let's assume the anabolic stimulation of a single PGF2 administration lasts for two hours. Of course, this figure depends upon the dosage: the higher the dose, the longer it lasts, as it will take more time for our body to degrade the prostaglandins. If you inject only twice a day, you will generate a total of four hours of intense anabolism per 24 hours. It means that 20 hours during the day are wasted. If you inject 5 times a day, you create 10 hours of intense anabolism per 24 hours.
Is this a strength or a weakness of PGF2 over steroids? You are exposed to steroids 24 hours per day (assuming you use injectables over orals). So, again steroids are more comfortable to use. But you may have noticed that the levels of most of our endogenous hormones fluctuate throughout the day. It prevents our muscles from downregulating their anabolic responses to the growth stimulating hormones. This is one of main the problem associated with the constant delivery of steroids. The time off PGF2 inherent in its short life cycle helps fight the tendency toward reduced anabolic response as time goes by. It is therefore a source of discomfort but also an advantage as far as results are concerned.
I am going to propose two schedules as examples. One will be for beginners who want to build up some lean muscles. The other is for more advanced bodybuilders who want to fill the gap between two steroid cycles.
The beginner schedule Inject PGF2 ex. (half a ml.) 30 minutes after the noon lunch. Inject the whole half a ml. at only one place. Your lunch should be high in proteins and carbs while low in fats. Make sure you have a serving of weight gainers at hand during the next two hours. This has two purposes. First, some people report a hypoglycemia-like feeling after PGF2. Of course this side effect should be countered. Eating a liquid meal generally makes them feel better. Second, whenever anabolism is elevated, so should be protein feeding frequency. Repeat a similar procedure after the evening meal. Change the side of injection. For the most daring, adding an insulin booster before the meals may be a good idea. ex. Glipizide (2.5 mg) but Glibenclamide (the insulin booster of reference) has been shown to lessen the incidence of side effects of PGF2 especially on the intestine. For Glibenclamide, start with the 1.25 mg pills and build up to the 2.5 mg. This makes it a smart stack to enhance anabolism while reducing side effects. Of course, you should be extra careful about the potential hypoglycemia so make sure you ingest some carbs every 30 minutes for the next two hours when it is time for the weight gainers. I suggest that you increase your creatine intake according to your PGF2 dosage as prostaglandins like most other anabolic substances accelerate the wasting of creatine. Go with at least 10 grams of creatine per day.
The advanced schedule
This is not a pro schedule. It should rather fit most of the readers' needs for muscles. As you taper off your steroid intake, slowly build up your PGF2 intake first in terms of dosage, then in terms of frequency. The animal studies suggest that PGF2 tends to depress testosterone secretion. But the PGF2 users usually get very "horny", which is a good sign, especially at the end of a steroid cycle. And do not discount the general hardening properties of PGF2 which amazingly is not restricted to skeletal muscles. Frequency of administration as well as dosage should be increased compared to beginners. You also have the choice between insulin injections and oral insulin boosters. Sticking with the oral booster may be wiser until you get more comfortable with the control of your glycemia. This is especially true as PGF2 will enhance the hypoglycemic effects of insulin. Wake up and have a liquid meal followed by a more solid meal within 30 minutes. Use that period for an insulin shot (start low with 5 UI and build up to no more than 15 UI per meal) or for oral Glipizide (2.5 to 5 mg). Prefer a long acting insulin to a short one. Wait for 15 minutes before your PGF2 (always start low and build up as you feel more comfortable). Repeat this procedure at lunch. Keep the liquid meal for after the lunch in case you feel hypoglycemia. Another reason to prefer Glipizide at that time is that you may get tired of the frequent injections. Repeat this procedure after training. You can use another PGF2 injection a bit before bedtime still with a meal but without the insulin or the booster. Some people who bad-mouth the prostaglandins argue that prostaglandins depress GH secretion. This is funny as the scientific literature points out the opposite. GH should be liberated overnight.
As you use more PGF2 than in the beginner cycle, go with at least 15 grams of creatine over 24 hours.
The science of cycling
The length of a PGF2 cycle is generally determined by default. The cycle usually lasts the whole time you want to be off steroids. It means it can go from between 24 hours to two months. Even though bodybuilders welcome a drug that allows them to grow while off steroids, most will get tired of using PGF2 after a while. They are usually happy to switch back to anabolics. A good rule of thumb is therefore to use PGF2 until you get tired of it. Again, there is no magic number here.
Yet many maintain a lighter intake of PGF2 centered around their weak bodypart. A lighter schedule includes one or two injections a day in a weak bodypart such as the calves to help bring them up but without having to go with all the trouble associated with normal PGF2 use.
To conclude, I again would like to quote Dan Duchaine about steroids in USH II:
"Rule #7: Most people who have taken massive amounts of steroids don't get sick, don't die, and don't go crazy.
Rule #8: ... Never assume that you are like 'most people' until you prove it."
This exact same rule apply to PGF2 users. Do not assume that PGF2 use is benign. PGF2 will affect every one of the cells composing your body. You are not immune from a rare, unexpected reaction. Please do not consider PGF2 usage lightly. We would not like to hear from you in the horror story section of a bodybuilding magazine.
Prostaglandins and their Discovery
Prostaglandins are part of a class of substances called eicosanoids. Eicosanoids are a group of substances derived from fatty acids and include prostaglandins, thromboxanes, and leukotrienes, all of which are formed from precursor fatty acids by the incorporation of oxygen atoms into the fatty acid chains. This reaction is called oxygenation and is carried out by cyclo-oxygenase enzymes. Prostaglandins and their metabolites have been found in virtually every tissue in the body.
The discovery of prostaglandins and determination of their structure began in 1930, when Raphael Kurzrok and Charles Lieb, both new York gynecologists, observed that human seminal fluid stimulates contraction of isolated uterine muscle. A few years later in Sweden, Ulf von Euler confirmed this report and noted that human seminal fluid also produces contraction in intestinal smooth muscle and lowers blood pressure when injected into the blood stream. It was Von Euler who came up with the name prostaglandin for this mysterious substance. The name prostaglandin seemed appropriate because he thought it originated in the prostate gland. Today, we know that prostaglandin production is not limited to the prostate, in fact, there is virtually no soft tissue in the body that doesn?t produce them. The name, however, has stuck with us through the years. If Von Euler had known his name for prostaglandins would still be with us into the next millennia, I?m sure he would have chosen to name them "Von Eulers" or "UVEs" instead of prostaglandins. By 1960, several specific prostaglandins had been isolated in pure crystalline form and their structures determined. Because our concern with prostaglandins involves primarily PGF2a, and perhaps PGE2, we will not go into detail about the myriad of other prostaglandins. Just know that prostaglandins are abbreviated "PG". The additional letter and numerical script indicate the type and series. The various types differ in the functional group present in the five-membered ring.
While scientists were studying the structure of these new compounds, other research was being done to determine their role in human physiology and their potential as drugs. Initially these compounds were extremely expensive to synthesize and/or isolate in sufficient quantities for research. In 1969, the price of prostaglandins dropped dramatically with the discovery that the gorgonian sea whip, or sea fan, is a rich source of prostaglandin-like materials. Now however, there is no need to rely on natural sources because chemists have developed highly effective laboratory methods for the synthesis of almost any prostaglandin or prostaglandin analog.
Thinking of using Lutalyse and/or PGF2A? I've been seeing this stuff pop up here and there and I'm not sure if people realize the potential hazards of this stuff?? Anyway.......if you have/are considering it......at least read this first:
Lutalyse:
Lutalyse is a veterinary drug that's coming into vogue with serious hardcore bodybuilders who'll stop at nothing to gain an "advantage" (even if it's not a real advantage). utalyse is made by Upjohn and is a prostaglandin (PGF2Aa).
PGF2a possibly mediates the endogenous insulin levels and is also a de facto thermogenic, as body temperature is increased after the administration of exogenous PGF2a. Unlike other fat burners, which only decrease the size of fat cells, PGF2a actually destroys them. Fat cells die when exposed to PGF2a.
Side effects associated with PGF2a use are an elevation in body temperature, vomiting, labored breathing and severe abdominal pain/cramping. As PGF2a vasoconstricts the blood vessels in the lungs, the user will feel a tightening in the chest. If you're an asthmatic, use of PGFa could very well put you into full respiratory arrest followed by death. Because PGF2a increases insulinogenic effects, hypoglycemia is a potential side effect.
PGF2a has a very short half-life in the body (only minutes) and most of it is metabolized in the lungs, thus making frequent injections necessary. PGF2a will almost always cause a very strong contraction of the intestine and bladder, emptying the stomach and intestines of all its contents. That's a nice way of saying you'll have explosive diarrhea.
Rumor has it that PGF2a will make training near impossible because of the pump that is created from this drug alone. One of the logistical drawbacks of PGF2a is the difficulty of administration. As it has such a short half-life, injections will be needed quite frequently. Lutalyse comes in a 5 ml (5 mg/ml) multi-dose vial. A single aspirin can render the effects of Lutalyse nonexistent, so most people who use this drug avoid aspirin and aspirin analogs.
Legit use of Lutalyse is by cattle farmers and ranchers. Farmers and ranchers will use this drug to induce abortions in barnyard animals. One-hundred percent of the idiots, uh, I mean, users, I spoke with told me that Lutalyse made them feel terrible. In short, this stuff could kill you, a lot faster that steroids ever could. I wouldn't suggest anyone try this stuff.
Is PGF2A for me?
Is PGF2A for everyone? Clearly not! Will it work? Yes! In this information, I will try to cover as much as possible about this drug. What I have put together here is based much upon personal experiences?. I feel no report can accurately prepare you for everything?. PGF2A is no exception!
PGF2A and Anabolism
Many studies have demonstrated an anabolic effect of PGF2A in skeletal muscles of both humans and animals. Paradoxically, PGF2A usage is still reserved to a bodybuilding elite and no one is willing to divulge the precious secret edge. One of the most remarkable effects of PGF2A is that it mediates the major part of the anabolic effects of insulin. By using PGF2A, you can use far less insulin and get a far stronger muscle building effect.
Is PGF2A safe?
The answer is clearly no, but neither is the use of steroids, insulin, clenbuterol, etc. By the way, PGF2A is invisible at any drug test. What kind of side effects to expect? The first ones -- if we except the elevation of temperature -- are that it will empty your guts of whatever they contain. So make sure you have unrestricted use of a bathroom. This is going to last around 20 minutes. What you do not want is to inject PGF2A into a vein! Learn to do the aspiration test. PGF2A is to be injected intramuscularly with an insulin needle if you are lean enough. This is going to hurt like #### and for a very long time (up to an hour) if you inject into a vein. You also may feel as if you had some kind of cold in your throat. It is due to the vasoconstriction effect PGF2A has in your lungs. Vomiting is a reported side effect but I have never heard of it in men.
PGF2A is not to be confused with steroids
You've probably realized by now that PGF2A produces growth in a radically different way from steroids -- although I do not exclude that part of the anabolic actions of androgens are mediated by a local release of PGF2A. The way PGF2A should be used is therefore radically different from that of androgens. Steroid use is rather comfortable. You inject or swallow them occasionally and wait for the growth to occur. This is not the case with PGF2A. Their main drawback is precisely their difficulty of administration. Steroids once injected survive several days in your body. PGF2A will last only several minutes though their stimulatory actions on anabolism will be far longer lasting (hours). It means that frequent injections are compulsory. Ideally, this would be five times per day, 30 minutes after meals.
You will also notice that once you have injected PGF2A, the muscle, which received it, gets sore almost immediately. If the muscle was already sore from training, that painful sensation may become very intense. You definitely do not want to repeat injections at the very same location, hence the necessity for rotation. Similarly, you will notice that you cannot inject in a muscle and then train this muscle. PGF2A is algesic (a pain mediator). Therefore, the timing of injections is key. You should wait for at least 2 to 3 days after you have trained a muscle to inject it. Then you will have to wait for 24 hours before training this muscle. If your muscle is already sore, I advise against using it as a site of injection as long as it hurts.
You will also learn that it is more comfortable to hit the outer part of the muscle than the inner part. For example, it is less painful to hit the outer head of the triceps than the inner head that touches your lats. Some bodyparts such as the biceps, the back, etc. are especially sensitive to the pain sensation PGF2A will induce.
PGF2A and Weak Bodyparts
The cardinal rule of PGF2A is to inject as far away as possible from the Intestine. You see, PGF2A induces a very strong contraction of the Intestine and the bladder (both smooth muscles). The major candidate as a site of injection was the front shoulder. But by repeating injections in the shoulders, bodybuilders soon ended up with grossly overdeveloped
Front delt's. They looked like walking monkeys. The rest of their body was growing too, but not as fast as the muscles closest to the sites of injections.
What this means is that if you want to develop a weak muscle, just inject PGF2A locally and watch! The muscle grows. We are talking about a real muscle growth and not an artificial swelling like Synthol or Esiclene would induce. Calves are a muscle of choice. In fact, even if your calves failed To grow no matter how much training you administered, PGF2A will
solve your problem. After a single cycle of PGF2A, unresponsive calves start to respond, even if they never did before!
The localized growth induced by PGF2A may appear magical, but there is a simple explanation. The life cycle of the injected PGF2A is terribly short (minutes). Most of it will .Be destroyed in your lungs. If you hit your right calf for example, this muscle will be exposed to a maximal concentration of PGF2A. As the prostaglandin rapidly leaks out of the calf and passes into the blood, it will quickly reach the lungs where most of it will be destroyed. What is left of the PGF2A will be dispatched evenly though you're whole body. It means that the other muscles will be exposed to far less of the anabolic effects of PGF2A. So unless you want to make a weak point grow, you should rotate the sites of injections frequently which is not a problem.
Grtz
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