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Originally posted by 2705
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Performance Effects: Oral GHB doses of 1-2 g have been shown not to deteriorate reactive, attentive and co-ordination skills related to driving, nor increase the effects of low dose alcohol. Similarly, oral doses of 12.5-25 mg/kg GHB had no effect on attention, vigilance, alertness, short-term memory or psychomotor coordination; although dizziness or dullness were experienced in 50-66% of subjects. It is important to note, however, that doses used in laboratory studies to date have been well below both recreational and abused doses of GHB.
Effects on Driving: Signs of behavioural effects and impaired performance have been reported in several driving case reports. In 13 driving under the influence cases where GHB was detected, the reported symptoms were generally those of a CNS depressant. The subjects were typically stopped because of erratic driving, such as weaving, ignoring road signs, and near-collisions. Common signs of impairment included confusion and disorientation, incoherent speech, short-term memory loss, dilated pupils, lack of balance and unsteady gait, poor coordination, poor performance of field sobriety tests, copious vomiting, unresponsiveness, somnolence, and loss of consciousness. GHB concentrations in blood specimens collected between 1-3.5 hours of the arrest ranged from 26-155 mg/L (median 95 mg/L). In another 11 cases of driving under the influence of GHB, concentrations of GHB in blood and urine specimens ranged from 81-360 mg/L and 780-2380 mg/L, respectively. Circumstances of their arrest, observed driving behavior and signs of impairment were similar to the previous study. Other reported symptoms have included dizziness, drowsiness, agitation, loss of peripheral vision, slow responses, slow and slurred speech, and transient unconsciousness.
bron: Drugs and Human Performance FACT SHEETS - Gamma-Hydroxybutyrate (GHB, GBL, and 1,4-BD)
Effects on Driving: Signs of behavioural effects and impaired performance have been reported in several driving case reports. In 13 driving under the influence cases where GHB was detected, the reported symptoms were generally those of a CNS depressant. The subjects were typically stopped because of erratic driving, such as weaving, ignoring road signs, and near-collisions. Common signs of impairment included confusion and disorientation, incoherent speech, short-term memory loss, dilated pupils, lack of balance and unsteady gait, poor coordination, poor performance of field sobriety tests, copious vomiting, unresponsiveness, somnolence, and loss of consciousness. GHB concentrations in blood specimens collected between 1-3.5 hours of the arrest ranged from 26-155 mg/L (median 95 mg/L). In another 11 cases of driving under the influence of GHB, concentrations of GHB in blood and urine specimens ranged from 81-360 mg/L and 780-2380 mg/L, respectively. Circumstances of their arrest, observed driving behavior and signs of impairment were similar to the previous study. Other reported symptoms have included dizziness, drowsiness, agitation, loss of peripheral vision, slow responses, slow and slurred speech, and transient unconsciousness.
bron: Drugs and Human Performance FACT SHEETS - Gamma-Hydroxybutyrate (GHB, GBL, and 1,4-BD)
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